updated by @rene: 02/23/17 09:33:47AM
Honestly, I do not really think it makes a difference too much. Because this is all about relaxation and having a little vacation from your mind and thoughts. I lay on the floor most of the time, this is most comfortable to me when I am stressed and need a mental break. Sometimes I sit up, but I always try to find a comfortable position that I can work with. Certain kinds of meditation I guess you do need to have a straight align, but unless you are doing those, do what is best for you and what feels best.
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I've have trouble these days with neck pain that makes it really hard. Lately I've decided that good enough is just going to have to do, since I'm never really comfortable. I think you can get used to using whatever position you set your mind to but it can be challenging. I don't think you have to be straightly aligned...just a position that keeps you from falling asleep and yet is comfortable enough that you can let go of the body.